250 Massachusetts Avenue
Laboratory in Cambridge, MA
At a glance
250 Massachusetts Avenue is a 517,029-square-foot laboratory building in Cambridge, Massachusetts, built in 2004. In its 2023 Cambridge benchmarking disclosure it reported a site energy-use intensity of 287.4 kBtu/ft² and 10,345 tCO₂e of greenhouse-gas emissions.
BEUDO · reporting year 2023
Benchmarking record
| Field | Value |
|---|---|
| ENERGY STAR score | — |
| Site EUI | 287.4 kBtu/ft² |
| Source EUI | 603.7 kBtu/ft² |
| GHG emissions | 10,345 tCO₂e |
| GHG intensity | — |
| Electricity | 24,495,836 kWh |
| Natural gas | 3,953 therms |
| Water use | 17,734 kgal |
| Gross floor area | 517,029 sq ft |
| Source record | cambridge:B1618:2023 |
The disclosure history
Year over year
| Year | Score | Δ | Site EUI | GHG emissions |
|---|---|---|---|---|
| 2023latest | — | 287.4 kBtu/ft² | 10,345 tCO₂e | |
| 2022 | — | 273.7 kBtu/ft² | 9,808 tCO₂e | |
| 2021 | — | 260.9 kBtu/ft² | 9,383 tCO₂e | |
| 2020 | — | 277.9 kBtu/ft² | 9,890 tCO₂e | |
| 2019 | — | 281.1 kBtu/ft² | 9,519 tCO₂e | |
| 2018 | — | 299.2 kBtu/ft² | 10,406 tCO₂e | |
| 2017 | — | 301.5 kBtu/ft² | 11,013 tCO₂e | |
| 2016 | — | 345.9 kBtu/ft² | 12,286 tCO₂e | |
| 2015 | — | 452.7 kBtu/ft² | 16,022 tCO₂e |
Compliance context
BEUDO
Cambridge's 2023 BEUDO amendments require non-residential buildings of 100,000+ sq ft to reach net-zero emissions by 2035 (reductions starting 2026) and those of 25,000–100,000 sq ft by 2050 (starting 2030).
Ownership
NOVARTIS INSTITUTES FOR
Own or manage this building? Claim it to correct the record and get compliance alerts.
Location
- Address
- 250 Massachusetts Avenue
- City
- Cambridge
- State
- Massachusetts
- Coordinates
- 42.36100, -71.09760
Within ~1 km
Nearby benchmarked buildings
- 250 Massachusetts Avenuescore —
Laboratory · 1,362,662 sq ft
- 32 VASSAR STscore —
College/University · 464,005 sq ft
- 555 Technology Squarescore —
Laboratory · 457,000 sq ft
- 43 VASSAR STscore —
College/University · 418,663 sq ft
- 70 PACIFIC STscore —
College/University · 362,687 sq ft
- One Hampshire Stscore 5
Office · 361,302 sq ft
See also: most efficient in Cambridge · biggest emitters
How does 250 Massachusetts Avenue compare with other laboratory buildings in Cambridge?
The latest disclosures cover 88 laboratory buildings in Cambridge, out of 902 buildings citywide. Its site EUI of 287.4 kBtu/ft² is roughly in line with the average of 272.6 kBtu/ft².
At 517,029 sq ft, it is about 185% above the average floor area of 181,468 sq ft for those buildings. It was built in 2004, 20 years later than the group's average year built (1984). Across all 24 jurisdictions BuildingCensus covers, the 795 laboratory buildings average an ENERGY STAR score of 29 and a site EUI of 231.7 kBtu/ft².
How has 250 Massachusetts Avenue's energy performance changed over time?
BuildingCensus holds 9 Cambridge disclosures for 250 Massachusetts Avenue, covering report years 2015–2023. Site EUI moved from 452.7 kBtu/ft² (2015) to 287.4 kBtu/ft² (2023), a 37% decrease. Reported emissions went from 16,022 tCO₂e to 10,345 tCO₂e over the same span (down 35%).
What does a site EUI of 287.4 kBtu/ft² mean?
Site energy-use intensity (EUI) is the energy a building uses on site in a year divided by its floor area, in thousand Btu per square foot — lower is more efficient. 250 Massachusetts Avenue's 287.4 kBtu/ft² across 517,029 sq ft works out to about 148.6 billion Btu (43,549 MWh-equivalent) in 2023. Its source EUI of 603.7 kBtu/ft² also counts the energy lost generating and delivering that power, which is why it is higher. The disclosure also reports 24,495,836 kWh of electricity, 3,953 therms of natural gas and 17,734 thousand gallons of water for the year.
Which law requires 250 Massachusetts Avenue to report its energy use?
250 Massachusetts Avenue reports under BEUDO, the legal basis of Cambridge's Building Energy Use Disclosure Ordinance (BEUDO), which publishes each covered building's annual benchmarking results. The record shown here is the report-year 2023 disclosure (source record cambridge:B1618:2023). Cambridge's 2023 BEUDO amendments require non-residential buildings of 100,000+ sq ft to reach net-zero emissions by 2035 (reductions starting 2026) and those of 25,000–100,000 sq ft by 2050 (starting 2030).
More laboratory buildings in Cambridge
- 303 Binney St· 480,000 sq ft · EUI 114.9 kBtu/ft²
- 222 Jacobs Street· 466,713 sq ft · EUI 154.8 kBtu/ft²
- 555 Technology Square· 457,000 sq ft · EUI 274.3 kBtu/ft²
- 301 Binney Street· 447,187 sq ft · EUI 259.5 kBtu/ft²
- 238 Main Street· 424,430 sq ft · EUI 184.9 kBtu/ft²
- 140 First Street· 408,259 sq ft · EUI 159.9 kBtu/ft²
- Laboratory buildings in Cambridge· 88 benchmarked
- All Cambridge benchmarked buildings· BEUDO
- Most efficient large buildings in Cambridge
- Least efficient large buildings in Cambridge
- Biggest emitters in Cambridge
Frequently asked questions
What is 250 Massachusetts Avenue's energy grade?
250 Massachusetts Avenue did not report an ENERGY STAR score in its 2023 disclosure, but its site energy-use intensity was 287.4 kBtu/ft².
How much energy does 250 Massachusetts Avenue use?
Its 2023 site energy-use intensity was 287.4 kBtu/ft² (603.7 kBtu/ft² source) across 517,029 sq ft, including 24,495,836 kWh of electricity and 3,953 therms of natural gas.
What are 250 Massachusetts Avenue's carbon emissions?
250 Massachusetts Avenue reported 10,345 tCO₂e of greenhouse-gas emissions for 2023.
Where is 250 Massachusetts Avenue?
250 Massachusetts Avenue is in Cambridge, Massachusetts. Its coordinates are 42.36100, -71.09760 (latitude, longitude), as published in the Building Energy Use Disclosure Ordinance (BEUDO) file.
How big is 250 Massachusetts Avenue and when was it built?
250 Massachusetts Avenue has 517,029 sq ft of gross floor area, as reported in its 2023 disclosure. The disclosure lists 2004 as its year built. It is classed as laboratory.
Is 250 Massachusetts Avenue covered by BEUDO?
Yes — it appears in the 2023 Building Energy Use Disclosure Ordinance (BEUDO) disclosure, which lists the buildings reporting under BEUDO.
Working with Cambridge building benchmarking records? Pro adds alerts, change history and CSV export ($49/mo); Enterprise adds full national files, the API and an MCP server for AI tools.
About this data
Source: Building Energy Use Disclosure Ordinance (BEUDO) (BEUDO), as published October 2, 2026. See the methodology for how records are matched, cleaned and scored.
Cite as: BuildingCensus, “250 Massachusetts Avenue, Cambridge, Massachusetts — 2023 benchmarking disclosure”, https://buildingcensus.com/buildings/cambridge/250-massachusetts-avenue-55b6fb2d (data as of October 2, 2026).