750 Main Street
Laboratory in Cambridge, MA
At a glance
750 Main Street is a 172,609-square-foot laboratory building in Cambridge, Massachusetts, built in 1910. In its 2024 Cambridge benchmarking disclosure it reported a site energy-use intensity of 219.2 kBtu/ft² and 2,358 tCO₂e of greenhouse-gas emissions.
BEUDO · reporting year 2024
Benchmarking record
| Field | Value |
|---|---|
| ENERGY STAR score | — |
| Site EUI | 219.2 kBtu/ft² |
| Source EUI | 414.9 kBtu/ft² |
| GHG emissions | 2,358 tCO₂e |
| GHG intensity | — |
| Electricity | 5,339,826 kWh |
| Natural gas | 196,191 therms |
| Water use | 4,714 kgal |
| Gross floor area | 172,609 sq ft |
| Source record | cambridge:B1605:2024 |
The disclosure history
Year over year
| Year | Score | Δ | Site EUI | GHG emissions |
|---|---|---|---|---|
| 2024latest | — | 219.2 kBtu/ft² | 2,358 tCO₂e | |
| 2023 | — | 188.2 kBtu/ft² | 2,042 tCO₂e | |
| 2022 | — | 55.1 kBtu/ft² | 587 tCO₂e | |
| 2021 | — | — | 0 tCO₂e | |
| 2020 | — | — | 0 tCO₂e | |
| 2019 | — | 6.9 kBtu/ft² | 78 tCO₂e | |
| 2018 | — | 10.4 kBtu/ft² | 124 tCO₂e | |
| 2017 | — | 10.8 kBtu/ft² | 136 tCO₂e | |
| 2016 | — | 10.5 kBtu/ft² | 132 tCO₂e | |
| 2015 | — | 10.6 kBtu/ft² | 136 tCO₂e |
Compliance context
BEUDO
Cambridge's 2023 BEUDO amendments require non-residential buildings of 100,000+ sq ft to reach net-zero emissions by 2035 (reductions starting 2026) and those of 25,000–100,000 sq ft by 2050 (starting 2030).
Ownership
MIT 750 MAIN STREET FEE OWNER LLC
Own or manage this building? Claim it to correct the record and get compliance alerts.
Location
- Address
- 750 Main Street
- City
- Cambridge
- State
- Massachusetts
- Coordinates
- 42.36280, -71.09630
Within ~1 km
Nearby benchmarked buildings
- 250 Massachusetts Avenuescore —
Laboratory · 1,362,662 sq ft
- 250 Massachusetts Avenuescore —
Laboratory · 517,029 sq ft
- 145 Broadwayscore 91
Office · 490,000 sq ft
- 303 Binney Stscore —
Laboratory · 480,000 sq ft
- 32 VASSAR STscore —
College/University · 464,005 sq ft
- 555 Technology Squarescore —
Laboratory · 457,000 sq ft
See also: most efficient in Cambridge · biggest emitters
How does 750 Main Street compare with other laboratory buildings in Cambridge?
The latest disclosures cover 88 laboratory buildings in Cambridge, out of 902 buildings citywide. Its site EUI of 219.2 kBtu/ft² is about 20% below the average of 272.6 kBtu/ft² — it uses less energy per square foot than the typical building in that group.
At 172,609 sq ft, it is roughly in line with the average floor area of 181,468 sq ft for those buildings. It was built in 1910, 74 years earlier than the group's average year built (1984). Across all 24 jurisdictions BuildingCensus covers, the 795 laboratory buildings average an ENERGY STAR score of 29 and a site EUI of 231.7 kBtu/ft².
How has 750 Main Street's energy performance changed over time?
BuildingCensus holds 10 Cambridge disclosures for 750 Main Street, covering report years 2015–2024. Site EUI moved from 10.6 kBtu/ft² (2015) to 219.2 kBtu/ft² (2024), an 1968% increase. Reported emissions went from 136 tCO₂e to 2,358 tCO₂e over the same span (up 1638%).
What does a site EUI of 219.2 kBtu/ft² mean?
Site energy-use intensity (EUI) is the energy a building uses on site in a year divided by its floor area, in thousand Btu per square foot — lower is more efficient. 750 Main Street's 219.2 kBtu/ft² across 172,609 sq ft works out to about 37.8 billion Btu (11,089 MWh-equivalent) in 2024. Its source EUI of 414.9 kBtu/ft² also counts the energy lost generating and delivering that power, which is why it is higher. The disclosure also reports 5,339,826 kWh of electricity, 196,191 therms of natural gas and 4,714 thousand gallons of water for the year.
Which law requires 750 Main Street to report its energy use?
750 Main Street reports under BEUDO, the legal basis of Cambridge's Building Energy Use Disclosure Ordinance (BEUDO), which publishes each covered building's annual benchmarking results. The record shown here is the report-year 2024 disclosure (source record cambridge:B1605:2024). Cambridge's 2023 BEUDO amendments require non-residential buildings of 100,000+ sq ft to reach net-zero emissions by 2035 (reductions starting 2026) and those of 25,000–100,000 sq ft by 2050 (starting 2030).
More laboratory buildings in Cambridge
- 700 Main Street· 168,879 sq ft · EUI 323.8 kBtu/ft²
- 399 Binney Street· 165,194 sq ft · EUI 192.2 kBtu/ft²
- 20 Acorn Park Drive· 164,481 sq ft · EUI 187.2 kBtu/ft²
- 101 Cambridgepark Drive· 161,040 sq ft · EUI 174.1 kBtu/ft²
- 100 Acorn Park Drive· 155,000 sq ft · EUI 123.4 kBtu/ft²
- 88 Sidney St· 145,275 sq ft · EUI 241.2 kBtu/ft²
- Laboratory buildings in Cambridge· 88 benchmarked
- All Cambridge benchmarked buildings· BEUDO
- Most efficient large buildings in Cambridge
- Least efficient large buildings in Cambridge
- Biggest emitters in Cambridge
Frequently asked questions
What is 750 Main Street's energy grade?
750 Main Street did not report an ENERGY STAR score in its 2024 disclosure, but its site energy-use intensity was 219.2 kBtu/ft².
How much energy does 750 Main Street use?
Its 2024 site energy-use intensity was 219.2 kBtu/ft² (414.9 kBtu/ft² source) across 172,609 sq ft, including 5,339,826 kWh of electricity and 196,191 therms of natural gas.
What are 750 Main Street's carbon emissions?
750 Main Street reported 2,358 tCO₂e of greenhouse-gas emissions for 2024.
Where is 750 Main Street?
750 Main Street is in Cambridge, Massachusetts. Its coordinates are 42.36280, -71.09630 (latitude, longitude), as published in the Building Energy Use Disclosure Ordinance (BEUDO) file.
How big is 750 Main Street and when was it built?
750 Main Street has 172,609 sq ft of gross floor area, as reported in its 2024 disclosure. The disclosure lists 1910 as its year built. It is classed as laboratory.
Is 750 Main Street covered by BEUDO?
Yes — it appears in the 2024 Building Energy Use Disclosure Ordinance (BEUDO) disclosure, which lists the buildings reporting under BEUDO.
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About this data
Source: Building Energy Use Disclosure Ordinance (BEUDO) (BEUDO), as published October 2, 2026. See the methodology for how records are matched, cleaned and scored.
Cite as: BuildingCensus, “750 Main Street, Cambridge, Massachusetts — 2024 benchmarking disclosure”, https://buildingcensus.com/buildings/cambridge/750-main-street-2eedc099 (data as of October 2, 2026).